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Qu R, Zhang W, Ma Z, et al

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To evaluate the effect of CI inhibition on growth, organoids were seeded as fragments in Matrigel and treated the following day with water (CTRL), 5 M 5FU, 3 mM metformin or a combination of 5FU and metformin for 72 h

The ultimate goal is to design CAR-T and CAR-NK cells capable of sustaining proliferation and cytotoxic activity within the hostile, high-ROS milieu of solid tumors while minimizing safety risks and maintaining immune tolerance

exercising muscle, and Na + /K + pumping rates

Importantly, KL7 also failed to reduce ROS/RNS in both infected and uninfected macrophages (Extended Data Fig