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Description

The second category includes disease management, controlling blood sugar in diabetic neuropathy, adjusting chemotherapy regimens, or treating underlying infections

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29,37 Norrin protein can also bind to Frizzled class receptor 4 (FZD4) and LRP5/6 to form a ternary complex and promote the downstream signal transmission of Wnt/-catenin

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280, no

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Both are dominated by gastrointestinal adverse events nausea, vomiting, diarrhea, constipation, and abdominal pain that are mostly mild to moderate and concentrate during dose escalation

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