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vascular endothelial growth factor (VEGF) receptor (VEGFR) antagonists such as apatinib

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In these interactions, there is a basal and physiological inflammatory environment induced by gut microbiota that allows the regulation of bacterial populations, preventing its spread [71]

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But none had been isolated with incretin-like properties first described by La Barre which was considered to be ideal for the treatment of type 2 diabetes (Marks Samols

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doi: 10.3389/fphar.2025.1709259 Received 19 September 2025 Revised 27 October 2025 Accepted 29 October 2025 Published 18 December 2025 Volume 16 - 2025 Edited by Vanessa Souza-Mello, Rio de Janeiro State University, Brazil Reviewed by Eduardo Duarte-Silva, University of Texas Health Science Center at Houston, United States Updates Copyright 2025 Cheng and Kim

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