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The latter is particularly important as it is closely linked to myocardial fibrosis, making cardiac MRI a valuable diagnostic tool for detecting and monitoring heart conditions [269]

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(3) Lysosomal Destabilization: CS compromises lysosomal membrane integrity, leading to the leakage of iron ions and hydrolytic enzymes into the cytosol

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Another randomized controlled trial assigned 20 head and neck cancer (HNC) patients undergoing cranial radiotherapy to receive either 20 mg melatonin or placebo, administered daily for six weeks post-radiotherapy

Reconstituting in 0.1 M ammonium bicarbonate or adding a few drops of dilute sodium hydroxide deprotonates acidic residues, improving solubility