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Putrescine promoted pigmentation in human skin explants and primary normal human epidermal melanocytes by inducing TYR, the rate-limiting enzyme in melanin synthesis [208]

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Therefore, the present review provides a comprehensive overview of potential therapeutic targets provided by ferroptosis-related pathways in stroke, providing new insights into how ferroptosis can be exploited to treat stroke

Miller RA, Harrison DE, Astle CM, Fernandez E, Flurkey K, Han M, Javors MA, Li X, Nadon NL, Nelson JF, Pletcher S, Salmon AB, Sharp ZD, Van Roekel S, Winkleman L, Strong R

2021), and transgenic mice are currently available for both the PTGS and ALOX pathway

Drugs metabolized via the CYP3A metabolic pathway interfere with CsA and tacrolimus metabolism, which can result in altered blood concentrations