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Diuresis On the last day of treatment, the animals were placed in acrylic metabolic boxes with water ad libitum to collect urine output for 12 h

[DOI] [PMC free article] [PubMed] [Google Scholar] Zhou FM, Wilson CJ, Dani JA, 2002

Specifically, the loss of glutaryl-CoA dehydrogenase leads to intracellular accumulation of glutaryl-CoA, promoting NRF2 glutarylation

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Stress-dependent alterations of E GSH caused by a transient draw of electrons from the glutathione redox buffer for oxidant detoxification and coupling of E GSH to target proteins thus may result in altered protein function and hence pronounced metabolic and developmental consequences for individual cells and the whole organism