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Although EGCG induces concentration-dependent DNA damage in human lymphocytes and Nalm6 cells, dietary doses rarely produce significant ROS formation or toxicity (Bertram et al

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The anorexia associated with cancer cachexia is likely caused by the activity of pro-inflammatory cytokines, such as tumor necrosis factor- (TNF-), interleukin-1 (IL-1), interleukin-6 (IL-6) and growth differentiation factor 15, that are produced either by the tumor or by the host in response to the tumor, which interfere with appetite signals within the anterior hypothalamus ( Undernutrition is a common problem in patients with cancer cachexia and can be a consequence of both reduced dietary intake, poor dietary quality and hypermetabolism ( For a long time, undernutrition and cachexia remained neglected medical conditions for which a clear therapeutic strategy was lacking

Available from: McLoone P, Toheeb Olalekan Oladejo, Kassym L, McDougall G

1.3 Exclusions: We cannot refund the kit if any of the following apply : The kit has been opened, used, or any seal has been broken