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In parallel, AOD 9604 has been shown to modulate enzymes involved in lipid synthesis, including acetyl-CoA carboxylase

The resulting ester group may then be hydrolyzed and converted into acyl azide with DPPA, followed by Curtius rearrangement with an alcohol, such as tert-butanol, to provide the corresponding N-Boc protected substrate (not depicted)

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B.TyagiS

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Parsons RB, Smith SW, Waring RH, Williams AC, Ramsden DB (2003) High expression of nicotinamide N -methyltransferase in patients with idiopathic Parkinsons disease