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The Tg2576 mouse model also carries human APP695 with the KM670/671NL mutation, driven by the hamster prion protein promoter

Neuroinflammation is one of the important factors contributing to neuronal damage and can also promote the inflammatory senescence of cells (Huang et al

Grisanzio, C

Cell response to ER-stress is called unfolded protein response (UPR

10.1111/j.1538-7836.2007.02540.x 53 du PlooyJ

Furthermore, nasal powders can be reconstituted in an aqueous buffer as a nasal solution or suspension to offer more flexible dosing according to specific clinical needs [16]