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Suppression of high glucose-induced cell proliferation in HepG2 cell line model by lutein was linked to increased expression of high glucose-mediated repressed HO-1 and prevention of hyperglycemia-mediated elevated ROS, but it was not associated with the induction of apoptosis

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Absence of intestinal microbiota does not protect mice from diet-induced obesity

J Pharm Negat Results 13:662669 Raheem AKK, Abu-Raghif AR, Zigam QA (2023) Cilostazol protects against Sepsis-Induced kidney impairment in a mice model

Therefore, while buprenorphine plasma levels will increase with repeated dosing (reaching an average concentration of 6.3 ng/mL and peak concentration of 11.8 ng/mL with 300 mg monthly at steady state [12]), a moderate and transient increase in peak plasma concentration up to 52% (17.9 ng/mL) is not expected to impact patients safety

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