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doi: 10.1177/0271678x221119292 38

Mechanistic investigation reveal that degradation is mediated by the ubiquitin-proteasome system, facilitated by covalent engagement with a E3 ligase, FBXO28, at cysteine 98

Other applications of the technique include the study of drug or hormone interactions with the binding proteins, the ability to concentrate substances present at low concentration and to separate the proteins based on their biological function

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