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HCQ diminished regulatory T cells (Tregs) in the peripheral blood of OLP patients, indicating a potential pharmacological mechanism ( Table 3 Other immune-related drugs in oral lichen planus

Biological agents are not cheap, and certain types of them may stimulate the hepatitis B virus and produce malignancies [46]

This phosphorylation cascade propagates signals that govern hepatocyte proliferation, survival, apoptosis, and inflammatory mediator production [39]

A landmark study that used affinity chromatography with ubiquitinsepharose to separate and reconstitute the E1E2E3 ubiquitin conjugation system, demonstrating that all three components are required for conjugation of ubiquitin to lysine residues in the substrate

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Meanwhile, they confirmed the SLC7A11 expression in the ARPE-19 cell line and the roles of its inhibitors on cell viability and function as well as the extent of lipid peroxidation, with the results suggesting that SLC7A11 can possibly represent a compelling target for therapeutic intervention in patients with neovascular AMD