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RAGE is a transmembrane receptor and is expressed in numerous tissues including ovaries, heart, lung and skeletal muscle, but also in monocytes, macrophages and lymphocytes [41]

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For example, decanoic acid (C10), a medium-chain fatty acid, enhances mitochondrial function and biogenesis via PPAR- activation and improves brain energy metabolism

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When triggered by peptides like -MSH or melanotan, these receptors start a process inside the cell that leads to increased melanin production

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A comparison of both structures revealed similar overall conformations

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Otto Warburgs contributions to current concepts of cancer metabolism

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