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Oral Melanotic Macule: Symptoms and Treatment Skinsight remove labial melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. melanotic spots Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Do Freckles on Lips Spell Sun Damage? 100% PURE Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review PMC

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