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These points track with broader physiology: Growth hormone secretion peaks during earlynight, slowwave sleep, and resistance exercise can raise growth hormone both in line with recovery and training adaptations

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ITC side chain lipophilicity should facilitate diffusion through lipid bilayer membranes, allowing access to the intracellular space 18 , and electron-withdrawing groups on the side chain may increase overall electrophilicity and reactivity of the N=C=S core 19

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