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GPX4 is 1 of 24 (25 in man) selenoproteins in mammals10 and is positioned at the top of the hierarchy of selenoproteins, i.e

Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro

In renal fibrosis, endoplasmic reticulum stress (ERS) activates iron-related apoptotic EMT through the XBP1-HRD1-NRF2 signaling pathway, offering new insights into mechanisms and potential treatments for EMT progression [105]