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However, it is possible that structural analogues of LCS3 that lack a nitro group are not metabolized by NQO1 and consequently fail to generate ROS via redox cycling and thus do not exhibit activity in cell-based experiments

Pharmacogn Rev 10(20):8489 Ardiana M, Pikir B, Santoso A, Hermawan H, Al-Farabi MJ, (2020) Effect of Nigella sativa supplementation on oxidative stress and antioxidant parameters: a meta-analysis of randomized controlled trials

Upon binding to arginine, SLC38A9 activates mTORC1 in a v-ATPase- and LAMTOR-dependent manner (Jung et al., 2015

for the Alliance for Clinical Trials in Oncology

10.3390/nu12092581 [PMC free article: PMC7551875] [PubMed: 32854403] [CrossRef] Hautanen V, Toimela T, Paparella M, Heinonen T (2023)

10.1016/j.toxlet.2017.07.215 Toxicol