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Description

Methods of identifying compounds that modulate the activity of the novel human HGPRBMY14 polypeptides and/or peptides are provided by the present invention and comprise combining a potential or candidate compound or drug modulator of GPCR biological activity with an HGPRBMY14 polypeptide or peptide, for example, the HGPRBMY14 amino acid sequence as set forth in SEQ ID NO:2, and measuring an effect of the candidate compound or drug modulator on the biological activity of the HGPRBMY14 polypeptide or peptide

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FOXO4-DRI has been suggested to prevent normal FOXO4 binding to p53, eliminate senescent cells, enhance organ function, and reduce cell death progression

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Cell Death Discov 9:182 Li Y et al (2023) Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis

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Adv Optical Mater 7:1900917 Wang G, Murray RW, Menard L, Nuzzo RG (2005) Near-IR luminescence of monolayer-protected metal clusters

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IL-17 and IL-22 are pivotal cytokines to delay wound healing of S

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Libraries were sequenced on the NextSeq 500 (Illumina, RRID:SCR_014983) using paired-end sequencing of 75 base pair reads by the Molecular Biology Core Facilities at Dana Farber Cancer Institute

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