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Furthermore, PKA phosphorylates and regulates the activity and expression of the cAMP-response element modulator (CREM) protein family, a group of transcription factors playing an important role in various cellular functions (82)

On the one hand, it reduces the avidity of importin for phenylalanine-glycine-rich nucleoporins (FG-nups), thereby facilitating the passage of import complexes through the permeability barrier

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Three of the sequences are very similar to each other (~96% sequence identity) and may represent transcripts derived from different homeologous alleles of the same gene (Figure S4)

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