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5.4 New Treatment Approches for DPN Recent advancements in DPN treatment focus on both symptom management and addressing underlying nerve damage through innovative pharmacological, non-invasive and regenerative approaches

The anti-inflammatory and repair mechanism usually activated in most inflammatory condition but when damage leads to severe inflammation or the agent persists in lungs, result in emphysema and fibrosis

Cold Spring Harb Perspect Biol (2014) 6:a016295

Whiddon, BB

MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Mild injection-site reactions Transient hunger (mild) Rare water retention Rare mild flushing Known interactions Concurrent rhGH not recommended Insulin / glucose-lowering agents (mild hyperglycemia possible) Contraindications Active malignancy Pituitary tumor Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved

Common Mistakes to Avoid Taking too much: Many believe that higher doses lead to faster results, but thats not true