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In sum, UA orchestrates diverse anti-cancer mechanisms from reconfiguring the tumor immune landscape and reversing multidrug resistance to provoking autophagy, and ferroptosis-driven cell death

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Arch Surg 130 : 11151122 Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S-I, Sameshima M, Hase A, Seto Y, Nagata S (1991) The polypeptide encoded by the cDNA for the cell surface antigen Fas can mediate apoptosis

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IECs derived from the lesional small intestinal mucosa of CD patients exhibited decreased expression of GPX4, which was paralleled by decreased enzymatic activity (Fig