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Curculigo orchioides ethanolic extract have positive effect against human breast cancer line (MCF-7) at 10 g/ml and cancer forming tissues and it is also known to have been one of the anti-carcinogenic herb [85, 86]

A review of the literature provides substantial evidence suggesting that AA is a tissue-specific immunological disorder

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In the past 10 years, ferroptosis, an iron-dependent form of regulated cell death, has become increasingly recognized as an important process that mediates the pathogenesis and progression of numerous cardiovascular diseases, including atherosclerosis, drug-induced heart failure, myocardial ischaemiareperfusion injury, sepsis-induced cardiomyopathy, arrhythmia and diabetic cardiomyopathy

In the human liver interactome, there is greater involvement of the proteins involved in lipid metabolism and various components involved in immune response activation and receptor-mediated endocytosis

Acknowledgments The authors acknowledges the use of Biorender that is used to create the figure