l carnitine nauda Liposomal L-Carnitine – NuEthix Formulations Carnitine 500 mg plus Co Q Nutrex L-Carnitine Liquid 3000 -

Carnitine analogs produced by the gut microbiota can colocalize with carnitine in the white matter of the brain and inhibit carnitine-mediated FAO in cell culture models of mouse CNS white matter, affecting the hosts nervous system, which provides a new perspective for understanding the complexity of the gutbrain axis [252]

Treatment: 1 RCT (n=240) suggests possible benefit for CIPN treatment (low certainty)

doi: 10.1038/jcbfm.2014.253 57

Impairment of excretion of AC occurs with deteriorating renal function leading to decreased carnitine clearance and resulting in elevated plasma levels of carnitine [13]

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Conference proceedings, FASEB