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In contrast to these former views, we will argue for a more complex interplay among heroin and its active metabolites: 6-MAM, morphine, and morphine-6-glucuronide (M6G)

K., Agarwal, N., Singh, P

Simultaneously, gastrointestinal dysfunction is a common feature of PD and could lead to the impaired absorption of L-DOPA, which also causes the motor fluctuations of PD (Svensson et al., 2016)

These results suggest that the phenomena of GSH depletion and MDA increase resulting from cellular oxidative stress might be concomitant with DON-induced ferroptosis