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WangYWangCZhuYChenKYuYLiRet al

ACS Cent Sci

doi: 10.31083/j.fbl2802038 25

2.1 Pathophysiology of Parkinsons disease 2.1.1 Mechanism of neurodegeneration PD is caused by the progressive degradation of dopaminergic nerve cells in the substantia nigra, a part of the brain that is essential for controlling movement (31)

Lipid peroxidation is trigger by the uptaking of hydrogen atoms located between two carbon-carbon double bonds in the lipid bilayer, resulting in the formation of a phospholipid radical at the center of the carbon chain