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Trexler and colleagues (2019a, 2019b) have recently questioned this mechanism, however, using the near-infrared spectroscopy (NIRS) technique to quantify blood flow

A core feature of these invisible illnesses is profound immune dysregulation, where the body's defense systems either fail to clear lingering threats or become hyper-reactive to everyday stimuli

Researchers examined factors like body temperature and oxygen levels during acute infection and their effects on immune and stress pathways, as well as neuropsychiatric symptoms in individuals with long COVID