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These factors include excess alcohol, hot drinks, spicy foods, smoking, stress, excessive exposure to sunlight, or extreme hot or cold temperatures, strong winds, some facial creams, including sunscreens, and cosmetics

Author contributions Authors responsible for concept and design were MJH, HTL, HYH, YL, and JHSP

Peptides are compact chains of amino acids that function as biological messengers

Sowers JR, Epstein M

The comprehensive KPV peptide benefits guide covers these mechanisms in greater detail, including the peptide effects on various inflammatory pathways

Clinical adverse events monitoring was done on each visit and complete laboratory check-ups (both haematological and biochemical) and ECG were repeated at the end of the study (12 weeks), so as to assess the safety of the study medication