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Disruption of gut barrier integrity may facilitate the translocation of metabolites such as short-chain fatty acids (SCFAs), bile acids, tryptophan derivatives, and lipopolysaccharide (LPS), which can modulate BBB function and neuroinflammatory responses [122]

Nat Rev Neurol 19:278288

Theres a significant difference between a product being developed by someone with a NASA background and a product incorporating NASA-owned technology, patents or technology-transfer agreements

Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment

Koinuma D, Tsutsumi S, Kamimura N, Taniguchi H, Miyazawa K, Sunamura M, Imamura T, Miyazono K, Aburatani H: Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling

Figure 11 Autoimmunity Upregulation of autoimmune genes As in other chronic disorders, some genes in ME/CFS patients have been found to be associated with autoimmunity, such as the HLA alleles (88), along with two other variants of HLA-DQB1 in combination with two RAGE-374A variants (489) was found