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Some are available over the counter, while others are available only by prescription

Any underlying medical issues would need to be treated

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For a 70 kg individual, this translates to approximately 1.75-28 mg per dose, though standard therapeutic protocols use significantly lower daily doses

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In each method solvents A and B comprising of water-acetonitrile-formic acid (90:10:0.1, v/v/v) and methanol-acetonitrile-formic acid (90:10:0.1, v/v/v), respectively were used