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Moreover, while the drafting of this paper was underway, a 10-week, randomized, placebo-controlled, double-blind trial to evaluate the effect of NMN supplementation on metabolic function in 25 postmenopausal women with prediabetes was reported 21 , in which NMN supplementation increased muscle insulin sensitivity, insulin signaling, and remodeling in women with prediabetes who are overweight or obese 21

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Phase II needs amino acids and other nutrients, including methionine, cysteine, glutamine, glycine, taurine, magnesium, glutathione, alpha-ketoglutarate, vitamins B5 and B12, vitamin C, folate, and choline