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10.4014/jmb.1904.04016 3

Nutrition and the Immune System of the Gut

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Recent studies suggest that exploring the metabolic changes in insulinoma may offer valuable insights into broader therapeutic strategies for various pancreatic tumors, as both insulinoma and PDAC exhibit shifts in glucose metabolism and are associated with diabetes [68]

The duality of CHAC1s role in cancer likely depends on the specific tumor microenvironment and interactions with other signaling pathways, such as the PI3K/AKT/mTOR or NRF2 pathways