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If you fish around the internet enough, you will find some anecdotal claims of insomnia and restlessness linked to excessive B12 intake, but direct causality has yet to be analyzed by experts

These unique structural and binding properties suggest that Class IIa HDACs exert their functions largely through deacetylase-independent mechanisms, relying on interactions with specific epigenetic modulators and transcription factors to regulate gene expression

This is called allodynia, or central sensitization, and is a common finding in chronic migraine

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