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Curr Neurovasc Res 10:247255 Starke RM, Thompson JW, Ali MS, Pascale CL, Martinez LA, Ding D, Chalouhi N, Hasan DM, Jabbour P, Owens GK et al (2018) Cigarette smoke initiates oxidative stress-induced cellular phenotypic modulation leading to cerebral aneurysm pathogenesis

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Apoptosis can be initiated via three principal pathways: the extrinsic (death receptor) pathway, the intrinsic (mitochondrial) pathway, and the endoplasmic reticulum (ER) stress pathway (Figure 2A)

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