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Tirzepatide: A novel cardiovascular protective agent in type 2 diabetes mellitus and obesity

Holthof LC, van der Schans JJ, Katsarou A, Poels R, Gelderloos AT, Drent E, et al

Over 250 pounds (113kg+): Maximum standard dosing of 500mcg applies, though some individuals may benefit from extending cycle length rather than increasing dose

B12 deficiency is far more common in older Americans

127 A randomized controlled trial found cocoa providing 750 mg of flavanols per day improved vascular function and markers of endothelial integrity more than low-flavanol cocoa after 30 days in subjects with coronary artery disease

Conditions like Downs or Turner syndrome, type 1 diabetes or thyroid problems can increase the likelihood of developing coeliac disease