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Yang RM, Fefferman RA, Shapiro CE

16 GunnessP.MuellerD.ShevchenkoV.HeinzleE.Ingelman-SundbergM.NoorF

Nature 585 , 113118 (2020)

The non-coenzyme action of thiamine in neurotransmission is further supported by the action of the thiamine analog oxythiamine, whose diphosphorylated derivative (oxyThDP), formed by TPK in vivo , is an antagonist of the coenzyme action of thiamine

Epithalon has been shown to regulate the expression of telomerase, an enzyme responsible for maintaining the length of telomeres, which play a crucial role in cellular aging and senescence