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Bioactive Materials, 32 , 502-513

Ethics declarations The Ethics Committee of Kashan University of Medical Sciences approved the study protocol (Registration No

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A scoping approach was selected given the anticipated heterogeneity of study designs, the predominance of preclinical literature, and the limited volume of human clinical outcome data

Injection-site & unknown long-term profile: Mild injection-site reactions can occur, and long-term human safety data are limited, so caution and monitoring are advised

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