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Therapeutic potential of cell-permeable PEP-1Srxn1 in mitigating oxidative and ischemic damage in the hippocampus

Nurmi, K

doi: 10.1002/fpf2.70036 197

See the KLOW research guide for composition

Reducing glutathione production in lymphoma cells, either through pharmacological inhibition of glutamate cysteine ligase (GCL), the enzyme catalyzing the rate-limiting step in glutathione biosynthesis, or via knockdown of GCLC , the GCL catalytic subunit, sharply decreased cell growth in 3D gels and xenografts