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Always check the spray's stated mcg-per-puff before splitting a daily total

NNMT is an enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide (NAM), producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH)

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Based on these data, experts recommend initiating studies with a conservative daily dosage of 0.5mg and before increasing to up to 1mg and 2mg daily, depending on the subject's tolerance and response