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Intracellular lipid levels additionally influence CMA activity

This process, where GSH acts as an electron donor, is vital in reducing disulfide bonds in cytoplasmic proteins to cysteines

doi: 10.2337/db09-055 279 CauchiSNeadKTChoquetHHorberFPotocznaNBalkauBet al

Assessment of Cellular GSH and GSSG Content To investigate the GSH and GSSG content in GSTP1 - and mock-transfected HepG2 cells, concentrations of total GSH and GSSG were measured using the GSH/GSSG-Glo TM Glutathione Assay kit (Promega, Madison, WI, United States)