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DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine)

Notably, the selenoamino acid metabolism pathway is downregulated in macrophages in inflamed CD biopsies

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Cells 9 , 2286 (2020)

, 36 , 1302-1315, doi: Yang, L., Venneti, S., and Nagrath, D

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