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AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart

Animal studies at effective doses showed no overt toxicity, but this cannot be extrapolated to human safety

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It has been reported that selenium interacts with metals such as gold, platinum, cadmium, cobalt and mercury, which in turn can counteract the toxicity of these heavy metals (140, 141)

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