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Published research consistently uses 98% purity material, and using lower-grade compounds would render any research results non-comparable to the published literature

Nov 2011;70(3):227-33

We do recommend you contact your insurance company to find out what their requirements are, as they change all the time

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Yen, Head of the Laboratory of Hormonal Regulation at Duke-NUS' Cardiovascular & Metabolic Disorders Programme, and senior author of the study, said, "The potential for using vitamin B12 and folate, which have high safety profiles and are designated as dietary supplements by the US Food and Drug Administration, as first-line therapies for the prevention and treatment of NASH could result in tremendous cost savings and reduce the health burden from NASH in both developed and developing countries." Professor Patrick Casey, Senior Vice-Dean for Research at Duke-NUS, said, "Currently, the only treatment for patients with end-stage liver disease is to receive a transplant

However, the conversion of folic acid to active forms of folate is relatively slow in human cells (98), and exposure to high amounts of folic acid through supplements and fortified foods leads to the measurable appearance of unmetabolized folic acid in the blood