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This work underscores the potential of host-directed therapeutics, in conjunction with antibiotics, to improve treatment outcomes

inhibition of ferroptosis can effectively attenuate secondary injury after ICH and play a neuro-protective role

However, individual results can vary based on factors like dosage, frequency, and skin type

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GPx reduce potentially damaging reactive oxygen species (ROS), such as hydrogen peroxide and lipid hydroperoxides, to harmless products like water and alcohols by coupling their reduction with the oxidation of glutathione ( Figure 2 ) (73, 74)

This section will explore these models in the context of ECD research, along with the recent emergence of complex microfluidic devices known as organ-on-a-chip systems (Fig