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Opioid-Induced Hyperalgesia and Allodynia Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain

10.1074/jbc.M509329200 197

the contribution of BPC 157 to Robert's cytoprotection that is, the ability to counteract fundamental alcohol-induced gastric lesions, which Robert called cytoprotection and the ability to counteract lesions arising from the direct injurious contact of the noxious agent with the cell represent the peripheral connection between the gut and the brain axis

Fatty acyl-CoA converted from FFA in the non-mitochondrial compartment is a substrate of -oxidation in mitochondria

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The activity of thioredoxin reductase (TrxR, EC1.8.1.9) was estimated using commercial kits (BioVision, Mountain View, CA, USA)