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Novel drugs for the management of hepatic encephalopathy: still a long journey to travel

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Given the evidence that a pulsatile pattern of GH secretion is important for many of its physiological actions, a strategy to augment physiological pulsatile GH secretion without inducing the side-effects of supraphysiological GH doses has been studied in HIV lipodystrophy with excess VAT and decreased endogenous GH secretion (144, 145)

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A study shown that the GABA-producing capacity of two strains of Lactococcus lactis in milk was increased by the addition of monosodium glutamate and by co-culturing with either Lacticaseibacillus rhamnosus or Lacticaseibacillus paracasei (52)

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