It has been found that cisplatin induces the generation of reactive oxygen species (ROS) in renal proximal tubule epithelial cells
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[6]-gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling

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Small amounts of RBD oligomers remaining from the ionic chromatography step were separated and removed by the subsequent size exclusion chromatography step, as illustrated in Supplementary Figures S5D, E