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doi: 10.1002/glia.10031 67 GuoS.MiyakeM.LiuK

10.1093/biolre/ioy058 469 WanJ.RenH.WangJ

However, the use of opioids for acute withdrawal is complicated when a patient lacks a clear diagnosis, as when he or she has no pain indication but uses illicit substances such as heroin

[4] [14] This depletion may result from increased oxidative stress, inflammation, and the metabolic burden placed on the liver by excess fat accumulation

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Those with medium to dark complexions have more active melanocytes, so they tan faster and retain pigment longer