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Patients with cystinuria, homocystinuria, or severe kidney disease should avoid supplementation without nephrologist oversight

Was a human pharmacokinetic study performed

Short-chain fatty acid: an updated review on signaling, metabolism, and therapeutic effects

104,105 A study demonstrated that oxidative stress-induced Nrf2 promotes drug efflux by upregulating ABCG2, as observed in biliary tract cancer cells

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There are plans to test butyrate supplements as well, given preclinical evidence that butyrate reduces demyelination and enhances remyelination in the CNS