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Here, we critically evaluate and discuss advances in development of currently reported transporter-utilizing (pro)drugs and nanocarriers in light of the main CNS pharmacokinetic principles

To induce acute peripheral sympathectomy, 6-OHDA powder (Sigma-Aldrich, 162957) was dissolved in sterile saline containing 1% ascorbic acid (Sigma-Aldrich, A4544) as an anti-oxidant and kept on ice and covered with foil before injection

Integrated Density was used instead of simple fluorescence values, as it represents the sum of the fluorescence contribution of each pixel within the selection, weighted by its area

Besides their therapeutic benefits, long-term oral probiotics offer protection for healthy women as well (Reid et al., 2003)

This limitation underscores the need for broader and more in-depth investigations into the relationships between environmental pollutants and urolithiasis in future work

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