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The combination leverages complementary mechanisms: amylin primarily delays gastric emptying and signals satiety through the area postrema, while GLP1 enhances pancreatic cell function and central appetite suppression [1]

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If nausea is persistent but not severe, dropping back one titration step for an additional 2 to 4 weeks before attempting the increase again often resolves the issue

Especially, considering the anastomosis as a particular intestinal wound that needs all processes to be accommodated before the healing of the anastomosis could occur (5-7, 9, 42, 43), the suggested particular effect on endothelium integrity, termed also "wound healing therapy", clearly covers the cysteamine colitis healing in the same way (5-7, 9)